Detalhe da pesquisa
1.
The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Nat Immunol
; 18(7): 744-752, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28553952
2.
Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
Nat Immunol
; 14(5): 514-22, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23563688
3.
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
J Immunol
; 199(7): 2249-2260, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28801357
4.
The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages.
J Immunol
; 195(1): 246-56, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26026062
5.
B-cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott-Aldrich syndrome.
Eur J Immunol
; 45(10): 2773-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26256668
6.
CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells.
J Immunol
; 193(7): 3492-502, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172502
7.
Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.
J Immunol
; 192(10): 4525-32, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711620
8.
Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.
Blood
; 119(19): 4395-407, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22431569
9.
Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.
Leukemia
; 36(1): 42-57, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34193976
10.
Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector.
Mol Ther Methods Clin Dev
; 20: 635-651, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33718514
11.
Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.
J Clin Invest
; 117(2): 407-18, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17218989
12.
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis.
Blood
; 112(10): 4158-69, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18687984
13.
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Front Immunol
; 10: 44, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30740104
14.
Activated CARD11 accelerates germinal center kinetics, promoting mTORC1 and terminal differentiation.
J Exp Med
; 215(9): 2445-2461, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30127060
15.
Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector.
Mol Ther Methods Clin Dev
; 4: 1-16, 2017 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28344987
16.
Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.
J Exp Med
; 212(10): 1663-77, 2015 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26371186
17.
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
J Clin Invest
; 123(5): 2024-36, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23619366
18.
WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.
J Exp Med
; 208(10): 2033-42, 2011 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21875954
19.
B cell intrinsic TLR signals amplify but are not required for humoral immunity.
J Exp Med
; 204(13): 3095-101, 2007 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18039950